Speaker articles

Take a look at what some of our Host-microbiome dynamics speakers have published recently and chat with them about their work in Bruges, Belgium.

Keynote speakers

Yasmine Belkaid, Institut Pasteur, France

Cell Press journal: Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness

Skin autonomous antibody production regulates host–microbiota interactions

Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis

Michael Fischbach, Stanford University, USA

Discovery and engineering of the antibody response to a prominent skin commensal

Mapping the T cell repertoire to a complex gut bacterial community

Cell Press journal: Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome

Session 1 speakers: Microbial cross-talk and community assembly

Kat Coyte, The Coyte Lab, University of Manchester, UK

Time delays modulate the stability of complex ecosystems

Reactivity of complex communities can be more important than stability

Kevin Foster, University of Oxford, UK

Cell Press journal: Metabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering

Microbiome diversity protects against pathogens by nutrient blocking

Horizontal gene transfer of molecular weapons can reshape bacterial competition

Benjamin H Good, Stanford University, USA

Cell Press journal: Unraveling the tempo and mode of horizontal gene transfer in bacteria

Cell Press journal: Abundance measurements reveal the balance between lysis and lysogeny in the human gut microbiome

Evolution of evolvability in rapidly adapting populations

Session 2 speakers: Host-microbial communication

Lindsay Hall, University of Birmingham, UK

Cell Press journal: Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts

Cell Press journal: Unlocking the power of human milk and infant feeding: Understanding how nutrition and early microbiota interaction shapes health programming

Ivaylo Ivanov, Columbia University, USA

Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases

Context-dependent role of group 3 innate lymphoid cells in mucosal protection

Cell Press, Immunity: Intestinal microbiota-specific Th17 cells possess regulatory properties and suppress effector T cells via c-MAF and IL-10

Cell Press, Cell: Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome

Susan Lynch, University of California, San Francisco, USA

The gut–airway microbiome axis in health and respiratory diseases

Early-life nasal microbiota dynamics relate to longitudinal respiratory phenotypes in urban children

Gut microbial bile and amino acid metabolism associate with peanut oral immunotherapy failure

Noah Palm, Yale University, USA

A host-microbiota interactome reveals extensive transkingdom connectivity

Cell Press journal: Highly multiplexed bioactivity screening reveals human and microbiota metabolome-GPCRome interactions

Session 3 speakers: Immune-microbial interactions

Bana Jabri, The University of Chicago, USA

Cell Press journal: Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis

Epithelial IFNγ signalling and compartmentalized antigen presentation orchestrate gut immunity

Cell Press journal: GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology

Dennis Kaspar, Harvard Medical School, USA

Structure of gut microbial glycolipid modulates host inflammatory response

Gut complement induced by the microbiota combats pathogens and spares commensals

Gut microbial fatty acid isomerization modulates intraepithelial T cells

Andrew Macpherson, University of Bern, Switzerland

Cell Press journal: Diet-derived LPS determines intestinal IgA induction and repertoire characteristics independently of the microbiota

Cell Press journal: Boundaries and integration between microbiota, the nervous system, and immunity

Cell Press journal: Plasticity of the adult human small intestinal stoma microbiota

Tiffany Scharschmidt, Scharschmidt Lab, University of California, San Francisco, USA

Staphylococcus aureus–specific skin resident memory T cells protect against bacteria colonization but exacerbate atopic dermatitis–like flares in mice

Cell Press journal: Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup

Cell Press journal: Early life host-microbe interactions in skin

Session 4 speakers: Microbiota in health and disease

Michael Howitt, Stanford University, USA

Cell Press journal: The Lost Kingdom: Commensal protists in the gut microbiota

Cell Press journal: Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition

Tuft cells mediate commensal remodeling of the small intestinal antimicrobial landscape

Iliyan Iliev, Weill Cornell Medicine, USA

Fungal symbiont transmitted by free-living mice promotes type 2 immunity

Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19

Cell Press journal: A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors

Session 5 speakers: Perturbing the system and therapeutic applications

Kenya Honda, Honda Lab, Keio University School of Medicine, Japan

Commensal consortia decolonize Enterobacteriaceae via ecological control

Diet-mediated constitutive induction of novel IL-4+ ILC2 cells maintains intestinal homeostasis in mice

The effects of oral microbiota on health

Sarah Leeber, University of Antwerp, Belgium

Cell Press journal: Host-independent synergism between Lactobacillus crispatus and other vaginal lactobacilli

Cell Press journal: Diversity in women and their vaginal microbiota

Citizen science as an instrument for women’s health research

Randy Platt, ETH Zurich, Switzerland

Multimodal scanning of genetic variants with base and prime editing

Transcriptional linkage analysis with in vivo AAV-Perturb-seq

Noninvasive assessment of gut function using transcriptional recording sentinel cells

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