Speaker

Pei-Hsuan Wu is an Assistant Professor in the Department of Genetic Medicine and Development at the University of Geneva, CH. Her lab investigates mammalian germline small RNAs in male reproduction, encompassing spermatogenesis and RNA-associated paternal influences. A main research focus is PIWI-interacting RNAs (piRNAs), which are essential for spermatogenesis and sperm function. Dr. Wu earned her bachelor’s degree in biology from Boston University, US. Following her undergraduate studies, she studied transcriptional regulation of mammalian metabolism as a research technician in Bruce Spiegelman’s lab at Harvard Medical School and Dana-Farber Cancer Institute. She investigated gene silencing by siRNA and miRNA using fly genetics and biochemistry during her Ph.D. training in Richard Carthew’s lab at Northwestern University, US. Dr. Wu then continued her RNA work in mammalian model systems and studied pachytene piRNA functions during her postdoctoral training in Phillip Zamore’s lab at the RNA Therapeutics Institute, University of Massachusetts Chan Medical School, US. Dr. Wu was awarded a career-starting grant by the Swiss National Science Foundation (PRIMA) and, in 2022, established her research group at the University of Geneva to research small RNA-mediated paternal contribution to embryogenesis, temporally resolve the functional requirement of the piRNA pathway in spermatogenesis, and leverage the genetic diversity among laboratory mouse strains to better understand male reproduction using mouse genetics, sequencing, biochemistry, and imaging techniques. She is currently an active member of the RNA Society, the Swiss Initiative for RNA & Disease (SIRD, formerly NCCR RNA & Disease) network, and the European Testis Workshop network.

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