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复旦大学代谢与整合生物学研究院以“双一流”建设为契机，建设全球顶尖的“代谢与整合生物学”研究机构为目标，推动代谢研究与细胞生物学、生物化学、遗传学、免疫学、神经科学、数理、工程以及临床研究等生命科学核心领域的交叉与整合研究，力争实现代谢及相关领域基础生物学研究的原创理论突破，同时在人类代谢相关疾病的基础研究与临床转化方面取得突破。
研究院与复旦大学生命科学学院、医学院、复旦附属医院、国外知名代谢研究院长期合作，以人类、模式动植物和微生物为研究对象，以代谢与遗传及发育的交叉研究为突破口，探讨代谢物感知和信号转导机制并揭示其对生命活动的调控机制，研究生物代谢过程的发生和发展机制。聚焦如下主攻方向与关键科学问题：1.代谢调控的分子和细胞生物学机制；2.代谢稳态调控与疾病发生；3.代谢研究新技术、新方法及临床转化。

Introduction of Institute of Metabolism and Integrative Biology (IMIB), Fudan University

The Institute of Metabolism and Integrative Biology (IMIB), Fudan University, takes the “double first-class” construction as an opportunity to build the world's top research institution for metabolism and integrative biology, and to promote cross-over and integrated research across the core fields of life sciences, such as metabolism, cell biology, biochemistry, genetics, immunology, neuroscience, mathematics, engineering, and clinical research. IMIB's aim is to achieve a breakthrough in the original innovative theory of basic biology research in metabolism and related fields, while achieving breakthroughs in basic research and clinical transformation of human metabolic related diseases.

IMIB has long-term cooperation with the School of Life Sciences, School of Medicine, Affiliated Hospitals of Fudan University, and the well-known foreign metabolic research institutes. With humans, model animals and plants, and microorganisms as the research objects, and the cross-research of metabolism, genetics and development as a breakthrough, IMIB works for exploring the mechanisms of metabolism biosensing and signal transduction, revealing their regulatory mechanisms for life activities, and studying the occurrence and development mechanisms of biological metabolic processes. IMIB focuses on the following main directions and key scientific issues: 1. The molecular mechanism of metabolic regulation; 2. The occurrence/development mechanism and intervention methods of metabolic homeostasis; 3. The development of relevant platforms and new technologies for metabolic and integrated biological research.

 

 

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