Organizing committee

Liang Ge received his bachelor’s degree from Shandong Normal University and his Ph.D. from the Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, under the supervision of Academician Baoliang Song. He then conducted postdoctoral research in the laboratory of Randy Schekman (2013 Nobel Laureate) at the University of California, Berkeley. He joined the School of Life Sciences at Tsinghua University at the end of 2017, and is currently a tenured Associate Professor.

Dr. Ge has long been devoted to membrane biology research.

Major Scholarly Contributions:

1. Discovery of the THU pathway, a molecular route for transmembrane translocation of non-classically secreted proteins, solving the key question of how signal peptide–lacking proteins enter the secretory pathway (Cell, 2020). He further elucidated the mechanism by which unconventional secretion bypasses the Golgi apparatus (Nature Cell Biology, 2024) and demonstrated that THU regulates intestinal epithelial differentiation and homeostasis by controlling IL-33 secretion (Cell Research, 2024).

2. Discovery of a new ERGIC–ERES interaction mechanism that regulates autophagosome biogenesis, answering an important question in the autophagy field regarding the membrane source and assembly of autophagosomes (Cell Research, 2022).

3. Identification of CCT2 as a novel autophagy receptor mediating the autophagic degradation of solid protein aggregates, providing a new therapeutic target for neurodegenerative diseases (Cell, 2022).

4. Discovery of two previously unknown autophagy pathways—RINCAA and RIMMBA—in Ras-mutant cancers, offering new targets for therapeutic intervention in Ras-driven malignancies (Cell Research, 2025).

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