The nervous system is a master regulator of physiological function across organs. This Cell Press Symposium provides a comprehensive overview of the latest developments in neural regulation and neural–organ interactions in health and disease, spanning feeding, energy homeostasis, and gut–brain axis, neuroimmune communication in both physiology and disease settings, including neurodegeneration and aging. Attendees will gain insights into the interaction between neural circuits and whole body metabolism and how factors such as genetics and lifestyle influence this connection.

Bringing together thought leaders from neuroscience, metabolism, immunology, genetics, and lifestyle, this symposium aims to foster cross‑disciplinary dialogue, collaboration, and translation to understanding how neural regulation sustains organismal homeostasis and where dysfunction contributes to disease.

• Central regulation of consummatory behavior and energy balance
• Central–peripheral communication in metabolic health
• Neural–immune interactions
• Metabolic regulation of neurodegenerative diseases/aging