Speaker articles

Take a look at recently published articles from our invited  speakers and organizers, and discuss their research with them at the symposium in Glasgow in June.

Keynote speakers

Judy Hirst, University of Cambridge, UK
Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes

Jared Rutter, University of Utah, USA
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Speakers

Kivanc Birsoy, Rockefeller University, USA
Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis

Jonathan Brestoff, Washington University in St. Louis, USA
Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood

Maria Falkenberg, University of Gothenburg, Sweden
Small molecules restore mutant mitochondrial DNA polymerase activity

Aleksandra Filipovska, University of Western Australia, Australia
Unique architectural features of mammalian mitochondrial protein synthesis

Lydia Finley, Memorial Sloan Kettering Cancer Center, USA
What is cancer metabolism?

Ana Garcia-Saez, Max Planck Institute of Biophysics, Germany
Mitochondrial pores at the crossroad between cell death and inflammatory signaling

Alexis Jourdain, University of Lausanne, Switzerland
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease

Natalie Krahmer, Helmholtz Diabetes Center, Germany
A spatiotemporal proteomic map of human adipogenesis

Tom MacVicar, Cancer Research UK Scotland Institute, UK
SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis

Heidi McBride, McGill University, Canada
Mitochondrial-derived vesicles in metabolism, disease, and aging

Laura Newman, University of Virginia, USA
Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal

Pere Puigserver, Harvard Medical School, USA
Liver mitochondrial cristae organizing protein MIC19 promotes energy expenditure and pedestrian locomotion by altering nucleotide metabolism

Luca Scorrano, University of Padua, Italy
Determinants and outcomes of mitochondrial dynamics

Hiromi Sesaki, Johns Hopkins University School of Medicine, USA
Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1

Hans-Georg Sprenger, Max Planck Institute for Biology of Ageing, Germany
Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST

Organizers

Isha Jain, Arc Institute and Gladstone/UCSF, USA
HypoxyStat, a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity

Thomas Langer, Max-Planck-Gesellschaft, Germany
Ribonucleotide incorporation into mitochondrial DNA drives inflammation