Speaker articles

Take a look at recently published articles from our invited speakers, and discuss their research with them at the symposium in Sitges in November

Keynote speakers

Johanna Joyce, University of Lausanne, Switzerland 
Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence
The evolving landscape of brain metastasis: volume II

Faisal Mahmood, Brigham and Women’s Hospital, Harvard Medical School, USA
Analysis of 3D pathology samples using weakly supervised AI

Speakers

Theodore Alexandrov, University of California San Diego, USA
HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics

Moran Amit, MD Anderson Cancer Center, USA
Integrating priorities at the intersection of cancer and neuroscience
Novel approaches to clinical trial design in cancer neuroscience

María Casanova Acebes, Centro Nacional de Investigaciones Oncológicas (CNIO), Spain 
Embracing diversity: macrophage complexity in cancer

Karin de Visser, Leiden University, the Netherlands 
Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread

Steven Josefowicz, Weill Cornell Medicine, USA 
Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity

Leeat Keren, Weizmann Institute of Science, Israel
Spatial profiling technologies illuminate the tumor microenvironment

Marlies Meisel, University of Pittsburgh, USA
Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
Toward a consensus on the tumor microbiota: Evidence, standards, and interpretation

Michelle Monje, Stanford Medicine, USA
The neuroscience of brain cancers
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice

Eytan Ruppin, Cedars Sinai Medical Center, USA
Enhanced prediction of breast cancer patient response to chemotherapy by integrating deconvolved expression patterns of immune, stromal and tumor cells

Charles Swanton, The Francis Crick Institute, UK 
Lung cancer in never smokers: from early detection to prevention
Longitudinal ultrasensitive ctDNA monitoring for high-resolution lung cancer risk prediction
Embracing cancer complexity: Hallmarks of systemic disease

Itay Tirosh, Weizmann Institute of Science, Israel
Cancer cell states: Lessons from ten years of single-cell RNA-sequencing of human tumors
Integrative spatial analysis reveals a multi-layered organization of glioblastoma

Timothy Wang, Columbia University, USA
A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis

Frank Winkler, Heidelberg University, Germany
Cancer neuroscience of brain metastasis: When in Rome, do as the Romans do

Jun Yu, The Chinese University of Hong Kong, Hong Kong
Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

Kun-Hsing Yu, Harvard Medical School, USA
Contrastive learning enhances fairness in pathology artificial intelligence systems

Zemin Zhang, Chongqing Medical University, China
Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity
A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer